The Prediction & Attention lab is based at the Centre for Cognitive Neuroimaging at the Donders Institute in Nijmegen, Netherlands.
The lab is headed by Dr. Floris de Lange.

Perception and decision-making are not automatic processes, but strongly shaped by internal brain states, which incorporate our goals, expectations, and knowledge about the world. The mechanisms by which these “top-down factors” affect perception, cognition, and behavior are still largely unknown. Where do the neuronal top-down signals come from? How do they change communication between sensory and decision-related brain regions? And how do these factors affect our perception and decision-making? These questions are the focus of investigation of the Prediction & Attention lab. We use a combination of behavioural and neuroimaging methods (MEG, fMRI, TMS) in healthy volunteers and clinical populations to examine how percepts and decisions are shaped by what we expect (prediction) and deem relevant (attention).

Recent key publications

  • Roelfsema PR, de Lange FP (2016). Early visual cortex as a multi-scale cognitive blackboard. Annual Reviews in Vision Science 2: 131-151. pdf
  • Kok P, Bains LJ, van Mourik T, Norris DG & de Lange FP (2016). Selective activation of the deep layers of the human primary visual cortex by top-down feedback. Current Biology, 26, 371-376. pdf
  • St John Saaltink E, Kok P, Lau HC, de Lange FP (2016). Serial dependence in perceptual decisions is reflected in activity patterns in primary visual cortex. Journal of Neuroscience, 36, 6186-92. pdf
  • Summerfield C, de Lange FP (2014). Expectation in perceptual decision-making: neural and computational mechanisms. Nature Reviews Neuroscience, 15, 745-56. pdf
  • Kok P, Jehee JFM, de Lange FP (2012). Less is more: Expectation sharpens representations in the primary visual cortex. Neuron, 75, 265-270. pdf


  • Paper accepted in Scientific Reports Kok P, van Lieshout LLF, de Lange FP (2016). Local expectation violations result in global activity gain in primary visual cortex. Scientific Reports, in press.
    Posted Nov 1, 2016, 1:49 AM by Floris de Lange
  • Paper accepted in Scientific Reports Lüttke CS, Ekman M, van Gerven MAJ & de Lange FP (2016). McGurk illusion recalibrates subsequent auditory perception. Scientific Reports, in press.
    Posted Aug 8, 2016, 5:48 AM by Floris de Lange
  • Biao Han obtains Fyssen post-doctoral grant Biao Han has obtained a Fyssen post-doctoral grant for a 2-year post-doctoral fellowship in the Prediction & Attention lab. Congratulations Biao!
    Posted Jul 18, 2016, 6:01 AM by Floris de Lange
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