The Prediction & Attention lab is based at the Centre for Cognitive Neuroimaging at the Donders Institute in Nijmegen, Netherlands.
The lab is headed by Dr. Floris de Lange.

Perception and decision-making are not automatic processes, but strongly shaped by internal brain states, which incorporate our goals, expectations, and knowledge about the world. The mechanisms by which these “top-down factors” affect perception, cognition, and behavior are still largely unknown. Where do the neuronal top-down signals come from? How do they change communication between sensory and decision-related brain regions? And how do these factors affect our perception and decision-making? These questions are the focus of investigation of the Prediction & Attention lab. We use a combination of behavioural and neuroimaging methods (MEG, fMRI, TMS) in healthy volunteers and clinical populations to examine how percepts and decisions are shaped by what we expect (prediction) and deem relevant (attention).

Recent key publications

  • Fritsche M, Mostert P, de Lange FP (2017). Opposite Effects of Recent History on Perception and Decision. Current Biology, 27, 1-6. pdf
  • Roelfsema PR, de Lange FP (2016). Early visual cortex as a multi-scale cognitive blackboard. Annual Reviews in Vision Science 2: 131-151. pdf
  • Kok P, Bains LJ, van Mourik T, Norris DG & de Lange FP (2016). Selective activation of the deep layers of the human primary visual cortex by top-down feedback. Current Biology, 26, 371-376. pdf
  • St John Saaltink E, Kok P, Lau HC, de Lange FP (2016). Serial dependence in perceptual decisions is reflected in activity patterns in primary visual cortex. Journal of Neuroscience, 36, 6186-92. pdf
  • Summerfield C, de Lange FP (2014). Expectation in perceptual decision-making: neural and computational mechanisms. Nature Reviews Neuroscience, 15, 745-56. pdf


  • Paper accepted in Journal of Neurophysiology te Woerd E, Oostenveld R, de Lange FP, Praamstra P (2017). Impaired auditory-to-motor entrainment in Parkinson's disease. Journal of Neurophysiology, in press.
    Posted Feb 6, 2017, 4:38 AM by Floris de Lange
  • Paper accepted in Nature Communications Ekman M, Kok P, de Lange FP (2017). Time-compressed preplay of anticipated events in human primary visual cortex. Nature Communications, in press.
    Posted Jan 30, 2017, 2:49 AM by Floris de Lange
  • ECVP2017 symposium on sequential dependencies in perceptual choice The symposium proposal "Unraveling Sequential Dependencies in Perceptual Choice" has been accepted for presentation at ECVP 2017 in Berlin. More information on the symposium below. Organizers:Tobias H. DonnerUniversity ...
    Posted Jan 9, 2017, 6:17 AM by Floris de Lange
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